We are taking a step forward and investigate whether adding a single dosage of creatine and guanidinoacetic acid (GAA) immediately before exercise session affects serum and salivary levels of GAA, creatine and creatinine.
We have continued scrutinization of L-carnosine in ABL! This time, we profile the single-dose pharmacokinetics of L-carnosine in healthy men in aim to compare the time course of its absorption, bioavailability, distribution, metabolism and excretion vs. traditional carnosine. The phase 0 study may help us to better determine the half-life of this nutritional additive and perhaps establish the most appropriate dosing regimen.
Kick off time for another RCT in elderly! This time, we aim to evaluate does 6-month supplementation with magnesium-powered hydrogen-rich water affect molecular and phenotypic biomarkers of aging. This ambitious trial, comprises various biomarkers of aging in men and women over 70 years, such as extensive blood biochemistry panel, brain metabolism, cognitive and physical function, even facial skin features, assessed both before and after the intervention in a magnesium-controlled parallel-group design.
Topical hydrogen in DOMS trial Questioning post-exercise recovery During the past few days, we started new trial evaluating the effects of topical hydrogen on biomarkers of delayed onset of muscle soreness (DOMS) after exhaustive eccentric exercise in young men. The small-scale double-blind placebo-controlled randomized trial actually tries to find out weather 30-min single-session bathing with super-saturated [...]
Does 8-plant extract affect telomerase activity? RCT trial in ABL We have started another double-blind RCT in our lab! This study investigates the effects of 6-week administration with 8-herb extract on exercise performance and metabolism, antioxidant status and telomerase activity in healthy men. Supported by Bio Aktivátor Kft (Hong Kong), this interesting study will help us [...]
Nitrates for exercise performance Placebo-controlled trial at ABL We just started another randomized controlled trial that evaluates possible performance-enhancing effects of novel formulation with nitrates. Supported by ThermoLife International LLC, this interventional study assess does a single dose of advanced nitrate formula improves cardiorespiratory endurance and muscular strength in young men, using a double-blind, placebo-controlled, cross-over [...]
Vasodilation study in ABL Kick-off day for a new trial Today, we have started a new research study that compares vasodilating effects of several dietary supplements. This exciting double-blind, randomized, cross-over trail evaluates the effects of single-dose intervention with different dietary supplements on muscle blood flow and brachial artery diameter before, during and after exercise in [...]
New studies with hydrogen ABL trials for ankle sprain and alertness Few days ago, we started two studies with molecular hydrogen, with both trials partly supported by our long-established industry partner HRW Natural Health Products Inc. In the first trial, we evaluate the effects of single-dose hydrogen-rich water and caffeine for improving alertness in sleep-deprived healthy [...]
Carnosine for multiple sclerosis Kick-off for an interventional trial with oral carnosine in multiple sclerosis This week, we have started a new interventional trial, evaluating the efficacy and safety of oral carnosine in patients with multiple sclerosis. During the next few months, we will evaluate does oral carnosine affect markers of brain bioenergetics and brain carnosine, [...]
Exercise and mitochondrial dysfunction Link between heavy prolonged exercise, health and biomarkers of mitochondrial function in athletic population As part of our project Novel Biomarkers of Fatigue and Mitochondrial Dysfunction, supported by the Provincial Secretariat for Higher Education and Scientific Research (Grant No. 114-451-710), our team starts to evaluate a possible connection between the prevalence of [...]