Targeting the brain with hydrogen

2021-02-05T11:24:13+01:00February 5th, 2021|News|

Clinical applications of molecular hydrogen seem to favorably affect obesity-related metabolic biomarkers in peripheral tissues, yet whether H2 directly tackles obesity pathways in the brain remains elusive. We summarized several molecular targets in the hypothalamus and beyond that could be altered by H2 gas in obesity in a new paper just published in Trends in Endocrinology and Metabolism.

Clinical Bioenergetics – 1st Edition

2021-01-30T14:08:38+01:00December 2nd, 2020|News|

The book on bioenergetics edited by Professor Ostojic has just been published for Elsevier! Clinical Bioenergetics: From Pathophysiology to Clinical Translation provides recent developments surrounding the etiology and pathophysiology of inherited and acquired energy-delated disorders. Across 40 chapters, world leaders in bioenergetics and mitochondrial medicine discuss novel methodologies designed to identify deficiencies in cellular bioenergetics

Brain creatine in preterm children

2020-11-05T23:27:52+01:00November 7th, 2020|News|

Creatine levels are rather sensitive to numerous conditions of the developing brain, including prematurity-related clinical complications. For instance, the presence of cerebellar injury in infants born prematurely was consistently associated with reduced concentrations of creatine (along with N-acetyl aspartate and choline), while cerebral cortical brain injury severity was inversely associated with both creatine and choline.

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