Creatine for chronic fatigue syndrome

This study evaluates the efficacy of 3-month supplementation with creatine to improve subjective indicators of fatigue, health-related quality of life and work capacity in adults with chronic fatigue syndrome, a debilitating and complex ailment characterized by profound fatigue of unknown cause.

Ideal participants will be:

• men and non-pregnant women older than 18 years
• who fulfilled CDC criteria for chronic fatigue syndrome
  • persistent fatigue of new or definite onset
  • not the result of ongoing exertion
  • not substantially alleviated by rest
  • results in substantial reduction in regular activities
• who have no psychiatric co-morbidity
• who reported no use of dietary supplements within 4 weeks prior to recruitment
• available for study period of ~ 6 months