Brain creatine in preterm children

ABL in Pediatric Research

Creatine levels are rather sensitive to numerous conditions of the developing brain, including prematurity-related clinical complications. For instance, the presence of cerebellar injury in infants born prematurely was consistently associated with reduced concentrations of creatine (along with N-acetyl aspartate and choline), while cerebral cortical brain injury severity was inversely associated with both creatine and choline. We discussed this and more in our new paper published in Pediatric Research few days ago, with the paper freely available here.