Applied Bioenergetics Lab
Advancing Science for Healthier Life
Disturbances in cellular energy homeostasis are considered a key element of different conditions – from cardiometabolic and neurodegenerative diseases to athletic performance and aging, with improving bioenergetics remains a challenging task for both industry and academia.
Here in Applied Bioenergetics Lab, we strive to advance novel dietary supplements and similar therapeutics that protect and restore tissue bioenergetics and metabolism in health and disease, by joint our forces with different partners.
Our lab is one of the most active research units at UNS, publishing 12-15 scientific articles per year in premier journals. Stay informed about our activities by clicking on the links below!
Latest news
Tackle aging and mitochondrial health
We just have started another randomized controlled trial with herbal extract PhytoDyNAmic! Now, we aim to explore the effects of 6-month supplementation with 8-herbs extract on mitochondrial function, telomere length, and chronic inflammation in men and women aged 65 years and older.
Stimulation of CT1 function
Upregulating CT1 by various agents could be perceived as an up-and-coming target in experimental and clinical nutrition, yet its clinical efficacy, safety and feasibility require a rather careful scrutinization in the forthcoming years.
Guanidinoacetic acid changes in schizophrenia
In a recent issue of Asian Journal of Psychiatry, we presented a pragmatic hypothesis that the inclusion of GAA might offer an additional benefit in profiling inflammation-oxidative stress in schizophrenia. GAA levels in the brain, cerebrospinal fluid, serum, and urine are responsive to various brain conditions.
Targeting the brain with hydrogen
Clinical applications of molecular hydrogen seem to favorably affect obesity-related metabolic biomarkers in peripheral tissues, yet whether H2 directly tackles obesity pathways in the brain remains elusive. We summarized several molecular targets in the hypothalamus and beyond that could be altered by H2 gas in obesity in a new paper just published in Trends in Endocrinology and Metabolism.
Nutraceuticals for AGAT Modulation
Our new paper published few days ago in Current Topics In Nutraceutical Research provides an update on specific nutraceuticals that are reported to modulate AGAT activity and discusses possible implications of targeting this enzyme in experimental and clinical nutrition.